[Readiness for intersectoral cooperation to preserve health of megalopolis population].

INTRODUCTION: For a better understanding of issues related to health-preserving activities for the benefit of city population, theoretical knowledge about the attitude and readiness of all interested parties for intersectoral cooperation is needed. The purpose of the study is to analyze readiness of the participants of health-preserving activities for intersectoral cooperation in Moscow. MATERIAL AND METHODS: In 2023, a one-time, one-time study of intersectoral responsibility, commitment and awareness, as well as satisfaction with individual health care (original test cards) was conducted among different participants in the health care of the population of the city of Moscow (n = 1007). From among them, participants were identified -workers of «medical¼ infrastructure facilities of urban space, participants-workers of other facilities (sports, culture, industry, waste disposal, transport, food, trade, education and others) and the population as a participant in intersectoral health saving. RESULTS: The research based on the original integrated assessment methodology shows insufficient readiness for intersectoral cooperation to implement health-saving activities for the benefit of Moscow population. Immature intersectoral responsibility, literacy, motivation for teamwork noted among the participants of the unified health-preserving city space determines the lack of internal conviction that it is necessary to deal with both own health, and health of other members of the urban community. CONCLUSION: The data obtained can form basis for new methodological approaches to prioritize control measures to improve intersectoral cooperation between the participants of health-preserving activities in the metropolis.

[Laboratory criteria of systemic inflammatory syndrome by surgical abdominal infections].

Results of treatment of 116 patients with acute appendicitis, cholecystitis pancreatitis and other inflammatory diseases of the abdominal cavity, complicated with peritonitis in 53 cases, are analyzed. The concentrations of interleukine-6 (IL-6), tumor necrosis factor small be, Cyrillic (TNF-6) and its soluble receptor in peripheral blood were used as systemic inflammatory response indicators. The increase of IL-6 and soluble TNF-6 receptor concentrations correlated with the augmentation of inflammatory response. The Willebrand factor with plasma activity of 180-200% can be used as an early indicator of inflammatory response in patients with acute abdominal diseases. The higher activity of the Willebrand factor is associated with multiple organ failure syndrome.

[Conceptual approaches to the organization of medico-social care of children]. / Kontseptual'nye podkhody k organizatsii mediko-sotsial'noi pomoshchi detiam.

Social economic crisis and decreased level of life tell on the health status of children. As primary health centers, pediatric outpatient clinics play the main role in the formation of healthy life style and rendering medicosocial care. However the existing system of organization of prophylactic care in pediatric outpatient clinics does not meet modern requirements, and problems of infant health care cannot be considered as purely medical. A draft program of restructuring local pediatric services is offered with consideration for modern social and economic problems.

[Functional state of peripheral blood neutrophils in children with rheumatism and borderline conditions]. / Funktsional'noe sostoianie neitrofilov perifericheskoi krovi pri revmatizme i pogranichnykh s nim sostoianiiakh u detei.

The authors discuss the effect of exotoxin of beta-hemolytic streptococcus (streptolysin-O) on the chemotactic activity of the peripheral blood leukocytes. 107 children with various forms of rheumatic fever and acute diseases of Streptococcal etiology and 18 healthy children were examined. The absence of the phenomenon of a specific chemotactic deactivation of polymorphonuclear leukocytes in response to streptolysin-O in healthy persons and in those suffering from rheumatic fever has been revealed. Sharply marked sensitization of polymorphonuclear leukocytes to streptolysin-O in patients with rheumatism increasing in the course of the disease and remaining in the inactive phase has been noted. The functional activity of polymorphonuclear leukocytes is characterized by chemotactic deactivation in response to streptolysin O that probably provides a favorable outcome of the disease.